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. Author manuscript; available in PMC: 2014 Oct 27.
Published in final edited form as: Int J Neuropsychopharmacol. 2014 Jan 22;17(6):907–916. doi: 10.1017/S1461145713001703

Fig 1. Structures of IVM, ABM and SEL.

Fig 1

Both IVM and ABM feature a spiroketal moiety with a mixture of isopropyl/isobutyl substituents. (A) ABM differs from IVM with the presence of an unsaturated double bond at the C22-23 position. SEL has three structural differences from IVM and ABM: (B) it has a cyclohexyl ring in place of the isopropyl/isobutyl substituent on IVM and ABM; (C) it has a ketoxime substituent in the place of the hydroxyl group of the tetrahydro- benzofuran unit on IVM and ABM; and (D) it lacks the second carbohydrate unit that is present in both IVM and ABM.