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. 2014 Jun 30;95(5):321–329. doi: 10.1111/iep.12089

Figure 3.

Figure 3

Infection of bone marrow chimeric mice with T. cruzi. Reconstitution of bone marrow chimeric mice was confirmed by flow cytometry analysis of GFP+ cells in the blood. (a), naïve mouse. (b), GFP-transgenic mouse. (c), chimeric mouse (one month after transplantation). One month after transplantation, chimeric mice were infected with 100 Colombian strain T. cruzi and treated with benznidazole (bdz) 28 days later. (d) Blood parasitaemia of T. cruzi-infected chimeric mice. Quantification of inflammation in the heart (e) and skeletal muscle (f) at various times after infection of chimeric mice. Data represent the mean ± SEM of 3–5 mice per group. ***P < 0.001.