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. 2014 Jul 1;171(20):4595–4619. doi: 10.1111/bph.12710

Table 8.

Sex differences in models of OCD and autism

Main behavioural index Male/female vulnerability Strength of evidence
Models of OCD
 Compulsive lever pressing Lever pressings No differences *
 8-OH-DPAT disruption of spontaneous alternation Alternation Undetermined *
 Marble burying Burying Undetermined *
 Deer mice Stereotypy No differences *
 ArKO mice Grooming/locomotion Males > females *
Models of autism
 Prenatal valproic acid Many indices Males > females *
Mthfr+/− Hyperactivity Males > females *
 Ehmt1+/− Social behaviour Males > females *
 BTBR T + tf/J Social behaviour Males > females **

Animal models of OCD and autism and the main behavioural index assessed is noted. Male and/or female vulnerability to the model is mentioned.

*

Denotes scarce evidence in the literature.

**

Denotes low strength of evidence in the literature.