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Guanfacine (GFC; 0.1 mg·kg−1) does not affect the behaviour of NK1R−/− mice in the EPM. (A) Time spent in the open arms; (B) number of entries to the open arms; (C) %time spent in the centre section number; and (D) number of entries to the closed arms of an EPM in wild-type (white bars) and NK1R−/− mice (grey bars). Data show mean ± SEM, N = 5. * P < 0.05.
