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. 2014 Sep 24;111(40):14542–14547. doi: 10.1073/pnas.1402814111

Fig. 6.

Fig. 6.

Schematic diagram showing the nucleotide and amino acid sequences of the encoded proteins and many other functions of the CCC RNA. Positions of initiation AUG codon (INI) and termination codons UGA (TER for 16 kDa) and UAG (TER2 for 18 kDa) are indicated. Locations of (+) and (−) hammerhead ribozymes are indicated. Positive-sense hammerhead ribozyme is shown in Inset A and that of minus-sense ribozyme is shown in Inset B. Arrowheads indicate the splice site for both ribozymes [on circular RNA depicting secondary structure and cleavage sites for both ribozymes (Insets)]. The amino acid sequences of 16-, 18-, and 23-kDa proteins are indicated. Shaded areas indicate the nucleotide sequences involved in (−) and (+) ribozymes. Nucleotide numbering starts at (position 1) UGAUGA.