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. 2013 Nov 28;5(4):382–391. doi: 10.1111/jdi.12156

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© 2013 The Authors. Journal of Diabetes Investigation published by Asian Association of the Study of Diabetes (AASD) and Wiley Publishing Asia Pty Ltd

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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(a) Dose‐dependent effects of ipragliflozin on mean changes in bodyweight levels from baseline over the study period. The values (means ± standard deviation) at each point are described in the figure. *P < 0.001 (compared with baseline by t‐test). (b) Changes in body weight from baseline to the end of treatment in drug‐naïve (n = 188) and drug‐treated patients (n = 172). Data are expressed as means ± standard error (SE). *P < 0.001 (compared with placebo by analysis of covariance). EOT, end of treatment.