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. 2014 Apr 14;15(5):489–507. doi: 10.1002/embr.201338390

Figure 1. Formation of operating RNP machineries for small RNAs and lncRNAs.

Figure 1

For both small RNAs and lncRNAs, specific RNA elements that determine their fate and functions are thought to be embedded in their primary transcripts. In the case of small RNAs, those RNA elements are recognized and cleaved by RNA-processing proteins into small RNA fragments, which are finally assembled into the operating RNP machinery. In contrast, RNA-binding proteins often remain associated with RNA elements in lncRNAs to form the RNP machinery.