Table 1. Initial values of the arachidonic acid/eicosanoid metabolic model.
| Symbol | AJ, control | AJ, DDC | B6, control | B6, DDC | PWD, control | PWD, DDC |
| PTGS1 | 1.00 | 2.13 | 1.00 | 1.41 | 1.00 | 2.09 |
| ALOX5 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| PTGDS | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| STAT3 | 1.00 | 1.41 | 1.00 | 1.42 | 1.00 | 2.03 |
| PKCD | 1.00 | 4.30 | 1.00 | 4.48 | 1.00 | 3.85 |
| GPX | 1.00 | 6.51 | 1.00 | 11.70 | 1.00 | 19.42 |
| PLA2 | 1.00 | 1.90 | 1.00 | 2.09 | 1.00 | 1.98 |
| ALOX5AP | 1.00 | 4.81 | 1.00 | 6.30 | 1.00 | 14.23 |
| ALOX15 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| PC* | 269.00 | 206.00 | 249.00 | 209.00 | 266.00 | 255.00 |
The enzyme concentrations of the control state were always initialized with 1.0 nM. The DDC initial value always reflects the fold change between the DDC-treated and the control expression value. The absolute concentration of phosphatidylcholine C33:2 (PC*) comes from MS-analysis and is measured in µM for control and DDC-treatment conditions of AJ, B6, and PWD mice.