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Comparison of ring conformations of mannopyranose substrates (red) extracted from cocrystal structures with mannosidases (n = 41), and the inhibitors (n = 50) swainsonine (SWA, green), deoxymannojirimycin (DMJ, blue), kifunensine (KIF, pink), noeuromycine (NOY, cyan), and mannoimidazole (MVL, yellow). Presumed transition states for mannosidases indicated by (*).
