TABLE 4.
Change in Percent Predicted Spirometry Parameters for an Interquartile Change in Urinary Phthalate Metabolite Concentrations by Age*
| Age 6–16 (n = 1642) | Age 17–49 (n = 1505) | |||||
|---|---|---|---|---|---|---|
| Urinary Phthalate | FEV1 | FVC | FEV1/FVC | FEV1 | FVC | FEV1/FVC |
| MnBP | −0.5 (−1.3, 0.3) | −0.9 (−1.6, −0.1) | 0.9 (−0.7, 2.6) | −0.8 (−1.7, 0.2) | −0.6 (−1.5, 0.2) | −0.3 (−1.0, 0.4) |
| MBzP | −0.6 (−1.5, 0.3) | −0.7 (−1.6, 0.2) | 0.0 (−0.5, 0.5) | −0.5 (−1.5, 0.6) | 0.4 (−0.6, 1.4) | −0.8 (−1.4, −0.2) |
| MCPP | −3.9 (−6.3, −1.4) | −1.0 (−1.8, −0.2) | −3.0 (−4.7, −1.4) | −0.8 (−1.7, 0.1) | −0.7 (−1.6, 0.2) | −0.2 (−0.8, 0.4) |
| MEP | −0.6 (−2.5, 1.3) | −0.8 (−2.1, 1.8) | −0.3 (−0.9, 0.3) | −0.7 (−1.5, 0.1) | −1.0 (−1.7, −0.3) | 0.2 (−0.4, 0.8) |
| ΣDEHP | −0.3 (−1.2,0.6) | 0.4 (−0.2, 0.9) | −0.7 (−1.6, 0.1) | −0.9 (−1.6, −0.2) | −0.8 (−1.5, −0.1) | −1.0 (−1.8, −0.2) |
*Results are adjusted for PM2.5, sex, smoking (current, occasional, and nonsmokers), fasting, income, and education. Italicized data show results considered statistically significant if 95% confidence limits do not encompass 0.
DEHP, di(2-ethylhexyl) phthalate; FEV1, 1-second forced expiratory volume; FVC, forced vital capacity; MBzP, mono-benzyl phthalate; MCPP, mono-3-carboxypropyl phthalate; MEP, mono-ethyl phthalate; MnBP, mono-n-butyl phthalate.