TABLE 5.
Change in Percent Predicted Spirometry Parameters for an Interquartile Change in Urinary Phthalate Metabolite Concentrations by Sex*
| Male (n = 1555) | Female (n = 1592) | |||||
|---|---|---|---|---|---|---|
| Urinary Phthalate | FEV1 | FVC | FEV1/FVC | FEV1 | FVC | FEV1/FVC |
| MnBP | −1.1 (−2.0, −0.2) | −1.0 (−1.8, −0.2) | −0.2 (−0.8, 0.4) | −1.0 (−2.0, 0.1) | −0.9 (−1.6, −0.2) | −0.3 (−1.0, 0.4) |
| MBzP | 0.8 (−1.5, 3.1) | 0.6 (−2.6, 3.6) | −0.1 (−1.3, 1.1) | −0.3 (−2.1, 1.5) | −0.6 (−2.4, 1.2) | 0.1 (−0.8, 1.0) |
| MCPP | −1.6 (−2.5, −0.7) | −1.4 (−2.3, −0.5) | −0.2 (−0.8, 0.4) | −0.6 (−1.4, 0.2) | −0.7 (−1.5, 0.1) | −0.5 (−1.2, 0.2) |
| MEP | −0.9 (−1.9, 0.1) | −1.1 (−2.0, −0.2) | 0.1 (−0.5, 0.7) | −0.1 (−0.9, 0.6) | −0.3 (−1.1, 0.5) | −0.0 (−0.6, 0.6) |
| ΣDEHP | −0.9 (−1.7, −0.1) | −1.1 (−2.1,−0.1) | −1.1 (−2.2, −0.0) | −0.6 (−1.4, 0.2) | −0.7 (−1.7, 0.3) | 0.2 (−0.3, 0.7) |
*Results are adjusted for PM2.5, age, smoking status (current, occasional, and nonsmokers), fasting, income, and education. Italicized data show results considered statistically significant if 95% confidence limits do not encompass 0.
DEHP, di(2-ethylhexyl) phthalate; FEV1, 1-second forced expiratory volume; FVC, forced vital capacity; MBzP, mono-benzyl phthalate; MCPP, mono-3-carboxypropyl phthalate; MEP, mono-ethyl phthalate; MnBP, mono-n-butyl phthalate.