Table 2. Enrichment Factors for an Inactive Model, Initial Active Homology Model, and Selected Nociceptin Receptor Conformationsa.
| enrichment |
|||||
|---|---|---|---|---|---|
| model | 2% | 5% | 10% | 15% | 20% |
| inactive model | 4.0 (8.0) | 4.0 (4.8) | 2.0 (2.4) | 1.6 (2.7) | 1.4 (2.0) |
| active model | 6.0 (14.0) | 4.8 (7.2) | 4.4 (4.8) | 3.5 (3.7) | 2.6 (3.4) |
| Model_01 | 18.0 (14.0) | 9.6 (8.0) | 5.2 (6.0) | 4.0 (5.1) | 3.8 (4.0) |
| Model_02 | 12.0 (14.0) | 7.2 (6.4) | 4.8 (6.0) | 4.3 (5.1) | 3.6 (3.8) |
| Model_06 | 12.0 (14.0) | 8.8 (8.0) | 5.2 (6.4) | 5.1 (4.0) | 3.4 (4.0) |
| Model_08 | 14.0 (14.0) | 8.0 (5.6) | 4.8 (4.4) | 3.2 (4.3) | 3.0 (3.8) |
| Model_09 | 8.0 (10.0) | 6.4 (7.2) | 5.2 (6.0) | 4.0 (5.3) | 3.0 (4.0) |
| Model_10 | 10.0 (8.0) | 6.4 (7.2) | 5.2 (6.0) | 4.0 (5.3) | 3.0 (4.0) |
| Model_11 | 14.0 (16.0) | 7.2 (8.0) | 5.6 (6.0) | 4.5 (4.8) | 8.4 (3.8) |
a
The numbers in the parentheses indicate the enrichment factors after combined methods (consensus of shape-based and docking-based enrichment).