Figure 4. IκB_NS does not regulate Il-17a gene expression.

(A) Relative IκB_NS mRNA expression levels in cultured CD4⁺ T cells under Th0 or Th17 conditions. IκB_NS mRNA expression in CD4⁺ T cells cultured under Th0 conditions from control mice was set to a value of 1. Data shown represent mean ± S.E. (n = 3) (B) Il-17a promoter activity presented as the fold-increase over that observed in HEK293 cells transfected with the empty vector. Data shown are the mean ± S.D. of duplicate samples and are representative of three independent experiments.