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. 2014 Oct 27;9(10):e111420. doi: 10.1371/journal.pone.0111420

Table 3. Effects of Removing Two Studies ([34] and Burton, unpublished) at High Risk of Bias from the Pooled Estimate of Generalized Stress-directed Training Program Effectiveness.

Outcome (number of studies) Pooled Std. MeanDiff,Random Effects(95% CI) P Value I2 Absolute Change in Effect Size and New Interpretation
Resilience
With Burton (13) 0.37(0.18, 0.57) 0.0002 41% 0.37 (0.18, 0.57) 0.0002 41% +0.04; suggests a highly significant, moderately consistent, and moderate effect on improving resilience
Without Burton (12) 0.41 (0.20, 0.61) <0.0001 40% 0.41 (0.20, 0.61) <0.0001 40%
Quality of Life
With Abbott (4) 0.34 (−0.03, 0.72) 0.07 10% +0.28; suggests a significant, highly consistent, and moderate effect on improving quality of life
Without Abbott (3) 0.62 (0.14, 1.09) 0.01 0%
Depression
With Abbott/Burton (6) −0.28 (−0.56, 0.01) 0.06 33% −0.23; suggests a highly significant, highly consistent, and moderate effect on improving depression symptoms
Without Abbott/Burton (4) −0.51 (−0.79, −0.22) 0.0005 0%
Stress
With Abbott/Burton (9) −0.28 (−0.60, 0.04) 0.09 57% −0.22; suggests a highly significant, highly consistent, and moderate effect on improving stress symptoms
Without Abbott/Burton (7) −0.50 (−0.74, −0.26) <0.0001 0%
Anxiety
With Abbott/Burton (5) −0.11 (−0.41, 0.20) 0.48 17% −0.26; suggests a borderline-significant, highly consistent, and small effect on improving anxiety symptoms
Without Abbott/Burton (3) −0.37 (−0.75, 0.01) 0.06 0%