Table 1. Intrinsic membrane and synaptic properties of Fs and Non Fs interneurons in sham-operated and lesion-treated mice.
Fs Sham | Fs Lesion | Non Fs Sham | Non Fs Lesion | |
Spike half-width | 0.345±0.011 ms (10) | 0.344±0.015 ms (9) | 0.623±0.015 ms (52) | 0.639±0.021 ms (48) |
Adapt. Coeff. | 0.774±0.019 | 0.798±0.042 | 0.451±0.013 | 0.477±0.017 |
Input resistance | 117.7±12.12 MΩ | 109.88±15.35 MΩ | 160.98±11.65 MΩ | 152.44±10.27 MΩ |
Max. firing rate | 315±23.59 Hz | 301±21.9 Hz | 102.08±8.8 Hz | 97.5±9.13 Hz |
Resting Vm | −67.20±1.99 mV | −69.22±1.99 mV | −70.13±0.98 mV | −66.12±0.90 mV |
sEPSC amplitude | 22.39±1.80 pA (10) | 17.34±1.12 pA (9) | 13.93±0.88 pA (33) | 13.36±0.54 pA (34) |
sEPSC frequency | 18.07±2.18 Hz | 17.82±1.72 Hz | 5.07±0.44 Hz | 7.99±0.73 Hz |
sEPSC rise time | 0.434±0.024 ms | 0.437±0.043 ms | 2.521±0.35 ms | 0.638±0.041 ms |
sEPSC decay time | 2.889±0.134 ms | 2.521±0.35 ms | 3.802±0.263 ms | 4.153±0.337 ms |
ECA/s | 6.61±1.09 nA/s | 5.02±0.61 nA/s | 5.96±0.64 nA/s | 9.05±0.96 nA/s |
PPR (20 ms) | - | - | 1.49±0.14 (9) | 1.20±0.07 (13) |
PPR (30 ms) | - | - | 1.32±0.06 (11) | 1.42±0.12 (14) |
PPR (50 ms) | - | - | 1.28±0.12 (10) | 1.29±0.11 (14) |
The numbers in parenthesis indicate the number of recorded neurons.