Fig. 3.

TNFAIP1/BACURD2 is a direct target of ERRα. (A) Summary of the RNA-sequencing analysis. Number of genes down- and up-regulated by each siERRα is displayed as well as the intersected lists. Lists of genes up- or down-modulated by the three siRNAs are available in Table S1. (B) Summary of Gene Ontology analysis. Genes commonly modulated by all siERRα were analyzed for molecular function and involvement in biological processes using GOEAST. Number of genes (n) and P values are shown for the relevant GO terms. Genes in common under terms GO:0031267 and GO:0016477 are listed. (C) Expression of BACURD2 protein in siRNA-treated cells with quantification relative to hsp90 and to control conditions.