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Inhibition of ROCK activity restores migration upon ERRα deficiency. (A) Cells treated with Y27232 (Y27) or vehicle were analyzed for MYPT1 and phosphoMYPT1 expression. Quantification (ratio P/t) indicates the ratio phosphoMYPT1/total MYPT1 relative to control conditions. (B) Control (shC) or ERRα-deficient (shE-4) cells, treated or not with Y27232, were analyzed by videomicroscopy in wound healing assays. Red cross represents the calculated mean arrival point.
