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Effect of furin inhibition on MERS-CoV S-mediated entry. Huh-7, MRC-5, WI-38, and Vero cells were pretreated for 2 h with dec-RVKR-CMK at increasing concentrations. The cells were then infected with wt MERSpp. Seventy-two hours postinfection, cells were lysed and luciferase activity was measured. Results are expressed as RLU, with error bars representing SD from the mean (n = 3). Data were analyzed using one-way ANOVA test.
