Fig. 2.

Increased intestinal permeability of AD subjects was associated with the persistence of psychological symptoms at the end of alcohol withdrawal. (A) Scores of psychological factors in CT and AD subjects at the beginning (T1) and end (T2) of withdrawal showing that AD subjects with high IP had higher score of depression, anxiety, and alcohol craving at T2. *P < 0.05 vs. CT; **P < 0.01 vs. CT; ***P < 0.001 vs. CT; ^$P < 0.05. (B) Associations of IP measured at T1 with psychological factors assessed at T2. Values are Pearson’s moment correlation coefficients. AD subjects with high IP and low IP are depicted in red and green, respectively. AD, alcohol-dependent; CT, control; IP, intestinal permeability.