Table 1.

Rolipram did not affect total fluid intake in the two-bottle choice test in mice.

Treatment (mg/kg)	H2O + 7% EtOH (ml)	H2O + 9% EtOH (ml)	H2O + 12% EtOH (ml)
Vehicle	2.83 ± 0.14	2.97 ± 0.14	2.98 ± 0.13
Rolipram 0.1	2.75 ± 0.20	2.95 ± 0.13	3.09 ± 0.14
Rolipram 0.25	2.95 ± 0.28	3.11 ± 0.38	2.96 ± 0.35
Rolpram 0.5	2.80 ± 0.30	2.70 ± 0.26	2.65 ± 0.19

Animals were provided with one bottle containing the ethanol solution at the concentration of 7%, 9%, or 12%, each for 3-4 d, and another bottle containing water. Rolipram (0.1, 0.25, or 0.5 mg/kg) or vehicle was injected twice daily. Total fluid intake, which was calculated as the sum of intake from both bottles, was not changed by rolipram at any of the three doses (p > 0.05). Data shown are means ± SEM; n = 8 - 10.