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. 2014 Nov;144(5):469–486. doi: 10.1085/jgp.201411222

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© 2014 Proks et al.

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Figure 1. — Nucleotide and sulfonylurea interactions with SUR. (A–D) Schematic showing interactions of nucleotides (A and B) and of nucleotides plus sulfonylureas (C and D) with SUR1 (A and C) and SUR2A (B and D). Minus signs indicate inhibitory effects; plus signs indicate interactions that stimulate channel activity.