Figure 1.

Acn is regulated on the protein level. (A) Schematic of acn locus and genomic transgenes all inserted at 96F3 for this study. RSB is the conserved RNPS1 and SAP18 binding site (Martelli et al., 2012). (B–E″) Projections of confocal sections of eye discs showing early stages of photoreceptor development. Regions of eye discs shown are just posterior to the furrow as in the white frame of Fig. 2 D. Images show wild-type discs stained for endogenous Acn (B) and DNA (B′) or discs with indicated transgenes stained for GFP (C and D) and DNA (C′ and D′) or for Myc (E) and GFP (E′). Arrows in E–E″ point to cells expressing GFP-KDEL but lacking Myc-Acn. Merged images are to the right. Bars, 20 µm. Detailed genotypes are given in Table S2.