Skip to main content
. Author manuscript; available in PMC: 2014 Oct 28.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Apr 29;30(7):1460–1466. doi: 10.1161/ATVBAHA.110.205526

Table 5. Odds Ratios for Future CAD Events by CCL2 polymorphism of study participants.

P* p p
−2835 C/A
 AA (ref) – CA – CC 1.00 (0.72 to 1.39) 0.90 (0.65 to 1.24) 0.429 0.129 0.352
 AA vs CA + CC 0.94 (0.69 to 1.29) 0.711 0.184 0.485
 CC vs CA + AA 0.90 (0.76 to 1.06) 0.193 0.064 0.157
−2578 A/G
 GG (ref) – GA – AA 1.03 (0.75 to 1.42) 0.93 (0.68 to 1.27) 0.448 0.209 0.437
 GG vs GA + AA 0.97 (0.71 to 1.32) 0.854 0.267 0.552
 AA vs GA + GG 0.90 (0.77 to 1.01) 0.210 0.100 0.898
−2136 A/T
 AA (ref) – AT – TT 1.05 (0.88 to 1.25) 0.89 (0.59 to 1.33) 0.720 0.498 0.652
 AA vs AT + TT 1.02 (0.86 to 1.21) 0.795 0.527 0.568
 TT vs AT + AA 0.88 (0.58 to 1.31) 0.517 0.459 0.897
−1811 A/G
 AG vs GG 1.20 (0.90 to 1.60) 0.222 0.076 0.071
−927 G/C
 GG (ref) – GC – CC 0.92 (0.77 to 1.10) 0.87 (0.56 to 1.29) 0.549 0.559 0.499
 GG vs GC + CC 0.91 (0.77 to 1.08) 0.288 0.934 0.309
 CC vs GC + GG 0.90 (0.61 to 1.32) 0.575 0.332 0.338
+764 C/G
 CC (ref) – CG – GG 1.06 (0.89 to 1.26) 0.91 (0.60 to 1.40) 0.725 0.499 0.570
 CC vs CG + GG 1.04 (0.88 to 1.23) 0.648 0.410 0.436
 GG vs CG + CC 0.90 (0.59 to 1.37) 0.619 0.577 0.903
+3726 T/C
 TT (ref) – TC – CC 0.97 (0.81 to 1.16) 1.29 (1.01 to 1.66) 0.064 0.254 0.083
 TT vs TC + CC 1.04 (0.88 to 1.23) 0.635 0.594 0.474
 CC vs TC + TT 1.31 (1.05 to 1.65) 0.020 0.098 0.026

Odds ratios and the corresponding 95% confidence interval calculated by conditional logistic regression, taking into account matching for age, gender, and enrollment time per CCL2 polymorphism.

*

P = Unadjusted p value.

P = p value adjusted for body mass index, waist circumference, systolic blood pressure and triglycerides;

P = p value adjusted for the Framingham Risk Score.