Table 1. Characteristics of study cohorts.
| FINRISK 1992 (N=5104) | FINRISK 1997 (N=6567) | FINRISK 2002 (N=7330) | Health 2000 (N=5123) | |
|---|---|---|---|---|
| Follow-up – yrs | 19 | 14 | 9 | 8 |
| Sex – no. (%) | ||||
| Men | 2287 (44.8) | 3005 (45.8) | 3299 (45.0) | 2371 (46.3) |
| Women | 2817 (55.2) | 3562 (54.2) | 4031 (55.0) | 2752 (53.7) |
| Age – yrs * | 43.9±11.3 | 46.8±12.9 | 47.5±13.0 | 50.0±11.7 |
| Cholesterol – mmol/l * | ||||
| Total | 5.6±1.1 | 5.5±1.1 | 5.6±1.1 | 5.9±1.1 |
| LDL | 3.5±1.0 | 3.5±0.9 | 3.4±0.9 | 3.8±1.2 |
| HDL | 1.4±0.3 | 1.4±0.4 | 1.5±0.4 | 1.3±0.4 |
| Blood pressure – mm Hg * | ||||
| Systolic | 135.1±19.3 | 134.9±19.5 | 134.8±19.9 | 132.7±20.1 |
| Diastolic | 81.1±11.9 | 82.1±11.2 | 79.0±11.4 | 82.2±11.1 |
| Body-mass index – weight(kg) / (height(m))2 * | 26.0±4.4 | 26.5±4.6 | 26.8±4.7 | 26.8±4.7 |
| Current smoker – no. (%) | 1425 (27.9) | 1606 (24.5) | 1928 (26.3) | 1611 (31.4) |
| Antihypertensive medication – no. (%) | 443 (8.7) | 761 (11.6) | 979 (13.4) | 953 (18.6) |
| Diabetes mellitus – no. (%) | 172 (3.4) | 323 (4.9) | 358 (4.9) | 291 (5.7) |
| Family history of cardiovascular disease – no. (%) | 1376 (27.0) | 2350 (37.8) | 2426 (33.1) | NA |
| Incident cases – no. (%) | ||||
| Cardiovascular disease | 501 (9.8) | 499 (7.6) | 291 (4.0) | 261 (5.1) |
| Coronary heart disease | 343 (6.7) | 344 (5.2) | 209 (2.9) | 197 (3.8) |
| Acute coronary syndrome | 235 (4.6) | 229 (3.5) | 148 (2.0) | 119 (2.3) |
*
mean±SD.
Abbreviations: N, number of individuals; LDL, low-density lipoprotein; HDL, high-density lipoprotein; NA, information not available