Table 5.

Association of the blood clinical parameters with blood gene methylation.

Blood Clinical Parameters	CD14			Et-1			HERV-W			iNOS			TNFα
	β *	SE	p-value	β *	SE	p-value	β *	SE	p-value	β *	SE	p-value	β *	SE	p-value
Triglycerides, mg/dL	−0.004	0.147	0.977	−0.002	0.060	0.972	0.026	0.041	0.533	−0.571	0.425	0.182	0.212	0.145	0.144
Homocysteine, µmol/L	0.036	0.140	0.797	0.056	0.056	0.324	−0.017	0.039	0.662	0.590	0.407	0.150	0.142	0.138	0.306
Cholesterol LDL, mg/dL	0.257	0.146	0.080	0.054	0.060	0.369	0.019	0.042	0.648	0.450	0.430	0.297	0.447	0.143	0.002
Cholesterol HDL, mg/dL	0.154	0.142	0.280	−0.016	0.058	0.782	−0.042	0.040	0.301	−0.014	0.418	0.974	−0.205	0.141	0.147
Total cholesterol/HDL ratio	0.092	0.144	0.525	0.050	0.058	0.392	0.042	0.041	0.307	0.327	0.420	0.438	0.467	0.139	0.001
LDL cholesterol/HDL ratio	0.087	0.143	0.541	0.067	0.057	0.247	0.044	0.040	0.273	0.78	0.417	0.366	0.445	0.138	0.002

Multivariable mixed-effect models adjusted for age, sex, BMI, smoking and % of neutrophils. * β regression coefficients were scaled to represent the increase in the dependent variable estimated for an increment equal to 1 SD in the independent variable.