Table 5.
EDF and adjusted R2 for trajectories of total, HDL, and total: HDL cholesterol ratio according to gender, and APOE allele status adjusting for age of menopause.
Model | Total Cholesterol | HDL Cholesterol | Total: HDL Cholesterol | |||
---|---|---|---|---|---|---|
EDF | Adjusted R2 | EDF | Adjusted R2 | EDF | Adjusted R2 | |
Gender | 0.25 | 0.19 | 0.20 | |||
Male | 6.2 | 3.0 | 4.5 | |||
Female | 7.3 | 4.2 | 4.3 | |||
Adjusted | 0.25 | 0.08 | 0.15 | |||
e2+ | 5.0 | 1.0 | 2.9 | |||
e3 | 7.1 | 4.2 | 4.6 | |||
e4+ | 5.5 | 2.6 | 3.1 |
Notes: Model for gender controlled for the effects of educational attainment, smoking history, average systolic and diastolic blood pressure, average blood sugar, restricted diet, average body mass index, use of cholesterol-lowering medications, and APOE allele status (n = 555). Adjusted model controlled for the effects of educational attainment, smoking, systolic and diastolic blood pressure, blood sugar, restricted diet, body mass index, APOE allele status, age of menopause, use of supplemental estrogen, and cause of cessation of menses (n = 335). Abbreviations: EDF = effective degrees of freedom; HDL = high density lipoprotein; APOE = apolipoprotein E.