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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Mol Med (Berl). 2014 Jan 25;92(5):473–485. doi: 10.1007/s00109-014-1120-y

Figure 2. ASM deficiency increases the expression of LC3B and p62 upon atherogenic stimulation.

Figure 2

Mouse CASMCs were under control condition or stimulated with 7-ketocholesterol (7-Ket, 10 μM) or rapamycin (RPM, 20 nM) for 24 hours. (A) Representative Western blot gel documents showing the protein expression of LC3B, p62 and β-actin in Smpd1+/+ or Smpd1−/− CASMCs. (B) and (C) are summarized data. *P<0.05 vs. Smpd1+/+ control; #P < 0.05 Smpd1−/− vs. Smpd1+/+ (n=6).