Table 2.
Distribution of clinicopathologic parameters according to median values S100A8/A9 positive cells in both intratumoral and peritumoral areas. (Chi-square test, *P < 0.05.)
| Parameters | S100 A8 (intratumoral) | S100 A8 (peritumoral) | S100 A9 (intratumoral) | S100 A9 (peritumoral) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| <123 (%) | >123 (%) | P* | <198 (%) | >198 (%) | P | <147 (%) | >147 (%) | P | <297 (%) | >297 (%) | P | |
| Age (years) | ||||||||||||
| <64 | 19 (55.9) | 15 (44.1) | 0.16 | 20 (58.8) | 14 (41.2) | 0.12 | 19 (55.9) | 15 (44.1) | 0.27 | 20 (58.8) | 14 (41.2) | 0.12 |
| >64 | 20 (43.5) | 26 (56.5) | 19 (41.3) | 27 (58.7) | 20 (43.5) | 20 (43.5) | 19 (41.3) | 27 (58.7) | ||||
| Gender | ||||||||||||
| Female | 17 (41.5) | 24 (58.5) | 0.54 | 15 (36.6) | 26 (63.4) | 0.32 | 16 (39) | 25 (61) | 0.07 | 16 (39) | 25 (61) | 0.08 |
| Male | 22 (56.4) | 17 (43.6) | 24 (61.5) | 15 (38.5) | 23 (59) | 16 (41) | 23 (59) | 16 (41) | ||||
| Size (cm)∗ | ||||||||||||
| <5.7 | 28 (63.6) | 16 (36.4) | 0.003 | 29 (65.9) | 15 (34.1) | 0.001 | 29 (65.9) | 15 (34.1) | 0.001 | 31 (70.5) | 13 (29.5) | 0.001 |
| >5.7 | 11 (30.6) | 25 (69.4) | 10 (27.8) | 26 (72.2) | 10 (27.8) | 26 (72.2) | 8 (22.2 ) | 28 (77.8) | ||||
| Grade∗ | ||||||||||||
| Low | 24 (68.6) | 11 (31.4) | 0.003 | 26 (74.3) | 9 (25.7) | 0.001 | 25 (71.4) | 10 (28.6) | 0.001 | 27 (77.1) | 8 (22.9) | 0.001 |
| High | 15 (33.3) | 30 (66.7) | 13 ( 28.9) | 32 (71.1) | 14 (31.1) | 31 (68.9) | 12 (28.9) | 33 (73.3) | ||||
| Depth of invasion | ||||||||||||
| T1 | 17 (65.4) | 9 (34.6) | 0.8 | 16 (61.5) | 10 (38.5) | 0.23 | 17 (65.4) | 9 (34.6) | 0.8 | 14 (53.8) | 12 (46.2) | 0.65 |
| T2 | 11 (55) | 9 (45) | 10 (50) | 10 (50) | 11 (55) | 9 (45) | 10 (50) | 10 (50) | ||||
| T3 | 6 (35.3) | 11 (64.7) | 8 (47.1) | 9 (52.9) | 6 (35.3) | 11 (64.7) | 9 (52.9) | 8 (47.1) | ||||
| T4 | 5 (29.4) | 12 (70.6) | 5 (29.4) | 12 (70.6) | 5 (29.4) | 12 (70.6) | 6 (35.3) | 11 (64.7) | ||||
| Lymph nodes∗ | ||||||||||||
| N0 | 20 (60.6) | 13 (39.4) | 0.001 | 20 (60.6) | 13 (39.4) | 0.01 | 20 (60.6) | 13 (39.4) | 0.003 | 19 (54.5) | 14 (45.5) | 0.01 |
| N1 | 16 (64) | 9 (36) | 14 (56) | 11 (44) | 15 (60) | 10 (40) | 14 (56) | 11 (44) | ||||
| N2 | 3 (13.6) | 19 (86.4) | 5 (22.7) | 17 (77.3) | 4 (18.2) | 18 (81.8) | 7 (31.8) | 15 (68.2) | ||||
| Distant metastasis∗ | ||||||||||||
| Absent | 16 (80) | 4 (20) | 0.001 | 12 (80) | 8 (40) | 0.001 | 15 (75) | 5 (25) | 0.007 | 14 (70) | 6 (30) | 0.007 |
| Present | 23 (38.3) | 37 (61.7) | 23 (38.3) | 37 (61.7) | 24 (40) | 36 (60) | 24 (40) | 36 (60) | ||||