Table 2.

Estimated Cox Proportional Hazard Ratios (95% Confidence Interval) of Incident Coronary Heart Disease by Quartiles of sdLDL-C, Nuclear Magnetic Resonance–Derived Small LDL Particle Concentrations, and LDL-C in Normoglycemic, Nondiabetic Participants (n=3334, 150 events) With Normal Fasting Glucose for an 8.5-Year Follow-Up Period

Quartile	LDL-C (0.52–7.3 mmol/L)	Small LDL-P (0–2018 nmol/L)	sdLDL-C (0.003–5.4 mmol/L)
1	Ref	Ref	Ref
2	0.85 (0.51–1.43)	0.78 (0.45–1.37)	1.45 (0.86–2.43)
3	1.50 (0.94–2.40)	0.90 (0.50–1.64)	1.56 (0.90–2.68)
4	1.75 (1.10–2.80)	1.37 (0.71–2.64)	2.41 (1.33–4.35)
	P=0.019	P=0.35	P=0.0037

Ranges for each analyte are specified. Analyses were adjusted for sex, systolic blood pressure, hypertension medication use, ethnicity, age (category), high-density lipoprotein cholesterol, and log triglycerides. Quartiles in which associations reached significance (P≤0.05) are shown in the table. LDL-C indicates low-density lipoprotein cholesterol; LDL-P, low-density lipoprotein particle; and sdLDL-C, small dense low-density lipoprotein cholesterol.