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. 2014 Sep 3;3(9):e133. doi: 10.1038/psp.2014.30

Figure 1.

Figure 1

Model structure for the subcellular level, including processes for antigen presentation in mature dendritic cells. The symbols in the figure legends are described below, with corresponding equation number in Supplementary Materials shown between parentheses. Inline graphic: Antigenic protein, including antigenic protein in plasma (Ag, Eq. 27 in Supplementary Material) and antigenic protein in the endosome: (AgE, Eq. 4 in Supplementary Material); Inline graphic: antigenic peptide in endosome (pjE, Eq. 5 in Supplementary Material); Inline graphic: competing protein in the endosome (cpE, Eq. 9 in Supplementary Material); Inline graphic: competing peptide in the endosome (cptE, Eq. 10 in Supplementary Material); Inline graphic: MHC-II molecules, including those in the endosome (MEk, Eq. 6 in Supplementary Material) and those on dendritic cell membrane (Mk, Eq. 13 in Supplementary Material); Inline graphic: antigenic peptide-MHC complex, including those in the endosome (pjMEk, Eq. 7 in Supplementary Material) and those on cell membrane (pjMk, Eq. 8 in Supplementary Material); Inline graphic: competing peptide-MHC complex, including those in the endosome (cptMEk, Eq. 11 in Supplementary Material) and those on cell membrane (cptMk, Eq. 12 in Supplementary Material).