Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Sep 3;3(9):e133. doi: 10.1038/psp.2014.30

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 American Society for Clinical Pharmacology and Therapeutics

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

PMC Copyright notice

Model structure for the cellular level, including cells, antigen, antidrug antibody, and B-cell receptor. The links between the three levels of the multiscale model are also illustrated to help interpretation. The acronyms are explained below, along with the corresponding equation number in the Supplementary Material shown between parentheses. MS: maturation signal (Eq. 1 in Supplementary Material); ID: immature dendritic (Eq. 2 in Supplementary Material); MD: mature dendritic (Eq. 3 in Supplementary Material); NT: naïve T (Eq. 14 in Supplementary Material); AT_N: activated T from naïve T (Eq. 15 in Supplementary Material); AT_M: activated T from memory T (Eq. 16 in Supplementary Material); MT: memory T (Eq. 17 in Supplementary Material); FT: functional T (Eq. 18 in Supplementary Material); NB: naïve B (Eq. 19 in Supplementary Material); AB_N: activated B from naïve B (Eq. 20 in Supplementary Material); AB_M: activated B from memory B (Eq. 21 in Supplementary Material); MB: memory B (Eq. 22 in Supplementary Material); P_S: short-lived plasma (Eq. 23 in Supplementary Material); P_L: long-lived plasma cell (Eq. 24 in Supplementary Material).