Table 1.
Formulation details of telmisartan liquisolid tablets.
| Formulation∗ | Vehicle | L f + | Avicel PH 102 (mg) | Aerosil 200 (mg) | Weight of tablet (mg)# |
|---|---|---|---|---|---|
| F1 | Transcutol HP | 0.247 | 340 | 17 | 417 |
| F2 | Propylene glycol | 0.224 | 375 | 18.75 | 453.75 |
| F3 | Polyethylene glycol 200 | 0.107 | 400 | 20 | 480 |
| F4 | Polyethylene glycol 600 | 0.101 | 500 | 25 | 585 |
| F5 | Tween 20 | 0.158 | 695 | 35 | 790 |
| F6 | Tween 80 | 0.139 | 610 | 30 | 700 |
*Fixed powder excipient ratio (R = Q/q) equal to 20 was used.
+Liquid load factor is defined as L f = W/Q.
#Final tablet weight includes 40 mg of disintegrant and 1% of lubricant.