Table 1.

Influence of astrocytes and OGD on mRNA expression of tight junction molecules of cerebEND cells.

	Normoxia	OGD	N-C6	OGD-C6
Claudin-3	1.00 ± 0.06	1.01 ± 0.11§	0.73 ± 0.05*#	0.82 ± 0.07
Claudin-5	1.00 ± 0.01	0.65 ± 0.08*§	1.04 ± 0.04#	0.55 ± 0.05*§
Claudin-12	1.00 ± 0.05	1.05 ± 0.05	1.02 ± 0.09	1.17 ± 0.09
Occludin	1.00 ± 0.02	0.38 ± 0.04*§	1.08 ± 0.11#	0.24 ± 0.02*#§
ZO-1	1.00 ± 0.05	0.74 ± 0.04*§	1.18 ± 0.11#	0.67 ± 0.07*§

Normoxia, cerebEND cells 4 h normoxia; OGD, cerebEND cells 4 h OGD; N-C6, cerebEND cells 4 h normoxia with C6-medium; OGD-C6, cerebEND cells 4 h OGD with C6-OGD medium. Data are presented as means ± s.e.m. (n = 8–10). Statistical significance was labeled with

^*vs. normoxia,

^#significant vs. OGD,

^§significant to N-C6 (p < 0.05, two-sided student's t-test with same variances).