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Characteristics of foam cell macrophages (FCMs) obtained from subcutaneous granulomas. Granuloma FCMs were isolated by flotation over a density gradient and differential adhesion from sponges implanted under the skin of ApoE KO or ApoE/Rag-1 DKO mice, as indicated. (A) In situ zymography (gelatinase activity, mean and SEM, n = 9–13). (B) Proliferative capacity (8 h BrdU pulse, mean and SEM, n = 8–14). *P < 0.05 vs. DKO, $P < 0.05 indicates gender differences for that genotype.
