Table 3.

Concentration of inflammatory and anti-inflammatory cytokines in plasma from ApoE KO or ApoE/Rag1 KO mice.

	Male ApoE KO		Male DKO		P-value (males)	Female ApoE KO		Female DKO		P-value (females)
	Mean	SEM	Mean	SEM		Mean	SEM	Mean	SEM
IFNγ	11.88	4.353	5.680	2.902	0.2440	11.33	6.345	6.012	2.595	0.6275
TNFα	297.4a	56.00	206.3	23.16	0.1495	167.9	21.46	191.0	19.26	0.4331
GM-CSF	118.0	24.55	106.4	16.66	0.6959	72.85	11.24	113.6	13.22	0.0304
IL-12p70	133.6	38.79	129.9	37.60	0.9457	58.65	12.61	127.7	29.90	0.0302
IL-10	15.23	3.023	23.99	3.852	0.0964	10.32	3.0.03	25.38	2.486	0.0012

Concentrations (picograms per milliliter) are expressed as mean and SEM, n = 9–10. Bold type indicates P < 0.05 for ApoE KO vs. DKO.

^aIndicates significant gender difference for that genotype.