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. 2014 Oct 28;4:151. doi: 10.3389/fcimb.2014.00151

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Copyright © 2014 Caswell, Oglesby-Sherrouse and Murphy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Regulatory redundancy and non-redundancy of bacterial sibling sRNAs. Individual sibling sRNAs are capable of controlling the expression of genes similarly to their sibling(s) (i.e., redundant regulation), but sibling sRNAs are also capable of regulating the expression of unique sets of genes as compared to their sibling(s) (i.e., non-redundant regulation). The schematic illustrates sibling sRNAs in red and blue, and their regulatory relationships to target mRNAs, depicted in black. (A) The OmrA and OmrB sibling sRNAs of Escherichia coli: A model for redundant sibling sRNAs. (B) The RfrA and RfrB sibling sRNAs of Salmonella enterica: a model for non-redundant sibling sRNAs.