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. Author manuscript; available in PMC: 2014 Oct 28.
Published in final edited form as: Langmuir. 2011 Sep 28;28(2):1068–1082. doi: 10.1021/la2028862

Figure 3.

Figure 3

Characterization of antibody-based biobarcode AuNPs by monitoring mass change of an antigen-coated quartz crystal during the addition of antibody and DNA-functionalized AuNPs (black) or DNA-only-functionalized AuNPs (gray). (A) Mass change of quartz crystals while flowing infected cells, PBS wash, BSA block solution, a second PBS wash and biobarcode AuNPs over the quartz crystal. (B) Normalized mass change after the addition of each biobarcode AuNP. Antibody and DNA-functionalized AuNPs but not DNA-only-functionalized AuNPs bind the antigen-coated quartz crystal. Reprinted with permission from Ref. 44.