. Author manuscript; available in PMC: 2014 Oct 28.

Published in final edited form as: Proc IEEE Int Symp Biomed Imaging. 2011 March-April;2011:2095–2098. doi: 10.1109/ISBI.2011.5872825

Table 1.

Summary of qualitative changes in multi-parametric MRI imaging parameters pre- and post-RT, and the corresponding quantitative features used by CADOnc^© to characterize each protocol.

	Pre-RT appearance	Post-RT appearance	CADOnc^© features
T2w	low T2w signal intensity in peripheral zone	Hypo-intense regions, smooth texture No change in residual CaP regions	1st order statistics, Kirsch/Sobel (gradients) 2nd order co-occurrence (Haralick)
MRS	elevated levels of A_ch reduced levels of A_cit	Nearly absent A_cit, polyamines in benign, CaP Residual CaP has elevated A_ch, A_cr	[A_ch, A_cr, A_cit, A_ch+cr/A_cit, A_ch/A_cr]
DWI	significantly low ADC compared to benign	Increased ADC in entire prostate compared to pre-RT Residual CaP lower ADC compared to benign areas	Raw ADC values, gradients 1st and 2nd order statistics