Table 2. Unadjusted and multiple-adjusted linear regression association of rs2282679 with vitamin D binding protein serum concentrations.

Model	Variable	Change in DBP (mg/l) (95% CI)	p-Value	r 2	F-Statistic
Univariable model (n = 2,248)	rs2282679 (C)	−27.6 (−30.4, −24.8)	3.3×10−76	0.14	368.7
Multivariate model (n = 2,247)	rs2282679	−27.4 (−30.0, −24.7)	1.3×10−84	0.26	197.3
	Female	29.2 (25.4, 32.9)	2.7×10−50
	Age—years	−0.6 (−0.7, −0.5)	3.4×10−26
	Age—decades	−6.2 (−7.3, −5.0)
	Non-European	−16.9 (−24.9, −9.0)	2.8×10−5

A fully expanded multivariate model for rs2282679 and DBP concentration including additional social factors and laboratory and clinical variables is available in Table S3.