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. 2014 Oct 28;9(10):e110967. doi: 10.1371/journal.pone.0110967

Table 6. The differential expression of genes regulated by M. bicoloratus bracovirus in the host ATM/p53 signaling pathway.

M/S
Gene family A_ID Function read_M RPKM_M read_S RPKM_S log2(Fold_change)normalized p-value Result S_ID M-ID
PPM1D comp23378_c0_seq1 protein phosphatase 1D 436 5.195890813 968 11.95154904 −1.201754598 4.38033E-50 down comp45971_c0_seq1 comp9608_c0_seq1
PTEN comp97411_c0_seq4 PTEN 233 1.759294286 911 7.126499544 −2.018196785 5.8123E-99 down comp59211_c2_seq7 comp62639_c0_seq1
TSC2 comp93326_c0_seq1 tuberous sclerosis 2 42 1.079341152 227 6.043807401 −2.48530675 1.25293E-32 down comp31311_c0_seq1 comp12675_c0_seq1
ATM comp98156_c1_seq4 ataxia telangiectasia mutated family protein 659 2.224231496 928 3.245023613 −0.544922026 2.64245E-13 comp56187_c0_seq2 comp18276_c0_seq1
ATR comp85208_c0_seq1 serine/threonine-protein kinase ATR 62 1.180743424 98 1.933593758 −0.71158922 0.00305328 comp53816_c1_seq1 comp15900_c0_seq1
CCNB comp86097_c0_seq2 cyclin B 984 4.996128296 1852 9.742149268 −0.963429564 1.7509E-66 comp57367_c0_seq1 comp19132_c0_seq2
CCND2 comp92629_c0_seq2 cyclin D2 1830 9.174971528 2968 15.41675056 −0.748723129 2.87139E-69 comp55005_c1_seq1 comp20586_c0_seq2
CCNE comp86772_c0_seq2 cyclin E 48 0.642601979 99 1.373128968 −1.095469805 1.62283E-05 comp29156_c0_seq1 comp130315_c0_seq1
CCNG2 comp81700_c0_seq1 cyclin G2 2216 12.41316031 3124 18.1300477 −0.546512258 3.78105E-42 comp58929_c0_seq2 comp21305_c1_seq2
CDK1 comp76441_c0_seq1 cyclin-dependent kinase 1 1207 7.410567531 2282 14.51560537 −0.969948801 1.51194E-82 comp27910_c0_seq1 comp16516_c0_seq1
CDK4 comp93505_c0_seq2 cyclin-dependent kinase 4 91 1.026690365 248 2.898845626 −1.497477356 9.30914E-19 comp46659_c0_seq1 comp104770_c0_seq1
CHK2 comp93714_c0_seq1 serine/threonine-protein kinase Chk2 116 1.042448685 212 1.973821482 −0.921015145 3.88281E-08 comp29305_c0_seq1 comp185379_c0_seq1
CYC comp93023_c0_seq1 cytochrome c 1 0.030570159 77 2.438730115 −6.317862227 1.87344E-19 comp96131_c0_seq1 /
EI24 comp94889_c0_seq2 etoposide-induced 2.4 mRNA 143 1.901385289 220 3.030624197 −0.672564063 2.18683E-05 comp87761_c0_seq1 comp67505_c0_seq1
GADD45 comp87685_c0_seq2 growth arrest and DNA-damage-inducible protein 933 10.69806017 999 11.86763536 −0.149683283 0.029048024 comp58271_c0_seq2 comp19840_c0_seq1
P53 comp63894_c0_seq1 p53 1659 10.61581334 2957 1.96E+01 −0.884896043 1.49E-91 comp27951_c0_seq1 comp20024_c0_seq1
RCHY1 comp94630_c0_seq1 RING finger and CHY zinc finger domain-containing protein 1 80 1.340540829 140 2.430487591 −0.858430608 2.87028E-05 comp30489_c0_seq1 comp128683_c0_seq1
RFWD2 comp93760_c0_seq1 E3 ubiquitin-protein ligase RFWD2 122 1.853497561 146 2.298054677 −0.310162907 0.094260381 comp99768_c0_seq1 comp10686_c1_seq1
RRM2 comp100970_c0_seq1 ribonucleoside-diphosphate reductase subunit M2 4699 44.24117718 6338 61.82281522 −0.482749578 1.81544E-67 comp61643_c0_seq1 comp10097_c0_seq1
SESN comp313998_c0_seq1 sestrin 12 0.967587612 0.5 0.041769028 4.533886815 0.000805877 / comp150130_c0_seq1
SIAH1 comp38385_c0_seq1 E3 ubiquitin-protein ligase SIAH1 886 4.980482149 1456 8.479580246 −0.767707437 4.40084E-36 comp189698_c0_seq1 comp20596_c1_seq1