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. 2014 Oct 28;9(10):e110545. doi: 10.1371/journal.pone.0110545

Figure 9. Elevation of IFN-α levels following Poly(I:C) administration.

Figure 9

IFN-α levels were examined in BALB/c mice sera. (A inset) Sera of uninfected naïve mice before (n = 2) and 24 h after poly(I:C) administration (n = 6). IFN-α in sera of 20 i.n. LD50 ECTV (A) infected untreated mice examined on days 4 (n = 6), 5 (n = 3) or 6 (n = 3) p.e. or 24 hours after treatment with VACV-Lister given on day 3, MVA on day 3, 4 or 5 or placebo treated on days 3, 4 or 5 (n = 3 in all groups). (B) IFN-α in sera of mice 24 hours after treatment with poly(I:C) on days 3, 4 or 5 given alone or in combination with VACV-Lister or MVA (n = 3–5/group).