Table 2. Survival Table – C57BL/6j mice.
Survival following treatment on: | Day 0 p.e. | Day 1 p.e. | Day 2 p.e |
Treatment | |||
Lister | 0% (0/11) | 0% (0/9) | N.D. |
Lister+poly(I:C) | 55% (6/11)*** | 45% (5/11)*** | N.D. |
MVA | N.D. | 72% (8/11)*** | 18% (2/11) * |
MVA+poly(I:C) | N.D. | 100% (11/11)*** | 55% (6/11)*** |
Poly(I:C) | 22% (2/9)** | 43% (6/14)*** | 27% (3/11)** |
Infected untreated C57BL/6j mice i.n. infected with ECTV (survived/total (n)): Exp.1 2LD50 (0/3); Exp.2 3LD50 (0/8).
*P<0.01, **P<0.001, ***P<0.0001 Log-rank (Mantel-Cox test) vs. infected untreated (0/11).
N.D. – not determined; p.e. – postexposure.