Table 1.
Relative mRNA expression levels of total Akt, Bad and Caspase3
| Total Akt | Bad | Caspase3 | ||||
|---|---|---|---|---|---|---|
|
|
||||||
| CON | SR | CON | SR | CON | SR | |
| 7D | 1.32 ± 0.09 | 0.58 ± 0.07* | 0.23 ± 0.04 | 1.12 ± 0.01# | 0.36 ± 0.05 | 0.69 ± 0.01 |
| 14D | 1.29 ± 0.05 | 0.36 ± 0.12* | 0.27 ± 0.02 | 1.34 ± 0.04# | 0.42 ± 0.06 | 0.92 ± 0.03§ |
| 21D | 1.36 ± 0.03 | 0.42 ± 0.06* | 0.21 ± 0.01 | 0.96 ± 0.02# | 0.33 ± 0.04 | 0.62 ± 0.04 |
CON, caged controls; SR, sleep restriction group; and D, days.
*
P < 0.05;
#
P < 0.05;
§
P < 0.05, compared with the matching caged control group.
Data are representative of three separate experiments performed in triplicates. Results are mean ± SEM.