Table 1.
Summary data of reported cases of colonic cryptococcosis
| Source, year | Age (years)/sex | Origin of report | Underlying disease/medication | Clinical presentations | Duration of onset | Dissemination | Colonic distribution | Endoscopic finding | Treatment and outcome |
|---|---|---|---|---|---|---|---|---|---|
| Zelman et al,26 1951 | 25/male | USA | CML, chemotherapy | Not mentioned | Not mentioned | Yes | Not mentioned | Ulcer | None → died |
| Unat et al,27 1960 | 16/male | Turkey | None | Diarrhea, abdominal pain, LGIB | 8 years | No | Descending colon | Mass | Surgery and amphotericin B → improved |
| Hutto et al,28 1988 | 29/female | USA | Job’s syndrome | Rectal abscess | 1 year | No | Perirectum, ascending colon | Stricture at ascending colon and perirectal abscess | Surgery and amphotericin B → improved |
| Van Calck et al,29 1988 | 47/male | Belgium | AIDS | Hematochezia, fever | Not mentioned | Yes | Perirectum | Perirectal abscess | Surgery, amphotericin B and flucytosine → improved |
| Daly et al,30 1990 | 63/male | USA | Cirrhosis, splenectomy, corticosteroids | Fever, chills, malaise | 7 days | Yes | Transverse colon | Mass | Amphotericin B and flucytosine → died |
| Bonacini et al,31 1990 | 31/male | USA | AIDS | Hemiplegia, seizure | Not mentioned | Yes | Not mentioned | Not mentioned | Amphotericin B and flucytosine → died |
| Washington et al,32 1991 | 38/male | USA | AIDS | Epigastric pain, odynophagia | 3 months | Yes | Cecum | Not mentioned | Antifungal therapy → died |
| Washington et al,32 1991 | 24/male | USA | Hodgkin’s disease | Not mentioned | Not mentioned | Yes | Not mentioned | Not mentioned | None → died |
| Washington et al,32 1991 | 31/female | USA | AIDS | Not mentioned | Not mentioned | Yes | Not mentioned | Not mentioned | None → died |
| Washington et al,32 1991 | 51/male | USA | Corticosteroids | Not mentioned | Not mentioned | Yes | Not mentioned | Not mentioned | None → died |
| Melato and Gorji,33 1998 | 84/female | Italy | None | Rectal bleeding | Acute | No | Sigmoid colon | Polyp | Polypectomy → improved |
| Law et al,34 2007 | 40/male | Canada | AIDS | Abdominal pain, diarrhea, dysphagia, fever | 6 weeks | Yes | Left colon | Multiple erythematous, raised, patchy lesions | Amphotericin B and flucytosine → improved |
| Song et al,35 2008 | 27/female | Korea | None | Melena | Not mentioned | No | Proximal ascending colon | Mass | Amphotericin B and fluconazole → improved |
Abbreviations: AIDS, acquired immunodeficiency syndrome; CML, chronic myeloid leukemia; LGIB, lower gastrointestinal bleeding.