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. 2014 Oct 21;7:1883–1890. doi: 10.2147/OTT.S64339

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© 2014 Qian et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Inhibition of Mus81 affects apoptosis of MCF-7 cells with 5-FU.

Notes: (A) Apoptosis of MCF-7 cells analysis was with combination FITC and annexin V and PI assay. (B) The apoptosis of MCF-7 cells increased in the siMus81 group in response to 5-FU (mean ± SD, n=3). (C) Apoptosis of T47D cells was analyzed by FITC-annexin V/PI assay. (D) The apoptosis of T47D cells did not increase in the siMus81 group in response to 5-FU (mean ± SD, n=3).

Abbreviations: 5-FU, 5-fluorouracil; FITC, fluorescein isothiocyanate; PI, propidium iodide; siCtrl, control siRNA; siMus81, Mus81 siRNA; SD, standard deviation; siRNA, small interfering RNA.