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Adverse effects of isoniazid preventative therapy for latent tuberculosis infection
| Adverse effect | Number of patients | Grade 3–4 severity |
|---|---|---|
| Any adverse effect | 56 | 6 |
| Any gastrointestinal | 21 | 2 |
| Hepatitis | 5 | 1 |
| Any dermatologic | 15 | 1 |
| Any rash | 15 | 1 |
| Acne | 8 | 1 |
| Alopecia | 0 | 0 |
| Any neuropsychiatric | 19 | 1 |
| Lethargy | 7 | 0 |
| Cognitive impairment | 9 | 0 |
| Peripheral neuropathy | 4 | 0 |
| Headache | 2 | 0 |
| Sleep disturbance | 1 | 0 |
| Depression | 1 | 0 |
