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. 2014 Oct 28;9(10):e111076. doi: 10.1371/journal.pone.0111076

Figure 6. Nkx2.2 controls Olig3 expression in V3 interneurons.

Figure 6

Transverse spinal cord sections from wild-type (A) and Nkx2.2−/− (B) embryos were subjected to immunolabeling with anti-Olig3 antibody. In E13.5 Nkx2.2 knockout mice, Olig3 expression was almost completely lost in ventral-most region of spinal cord. Arrows indicate the region in which Olig3 expression is affected. (C) The number of Olig3+ cells in the ventral-most region of E13.5 wild type and Nkx2.2−/− spinal cords. p<0.001. The dorsal part is up. Bars, 100 µm.