. Author manuscript; available in PMC: 2015 Nov 1.

Published in final edited form as: Arthritis Rheumatol. 2014 Nov;66(11):3170–3177. doi: 10.1002/art.38814

Table 5.

HLA-class I and II allelic frequencies associated with generalized morphea

Allele	Controls^†	Generalized	Odds Ratio (95% CI)	p-value ^*

Class II
DRA1^*15	246/1001 (25%)	23/58 8(40%)	2.0 (1.2 – 3.5)	0.010
DRA1^*15:01	185/1001 (18%)	21/58 (36%)	2.5 (1.4 – 4.4)	0.0009
DQA1^*03:00	0/1002 (0%)	11/38 (29%)	N/A	< 0.0001
DQA1^*02	353/1002 (35%)	30/58 (52%)	2.0 (1.2 – 3.4)	0.011
DQA1^*02:01	205/1002 (20%)	22/58 (38%)	2.4 (1.4 – 4.1)	0.002
Class I
C^*08	31/579 (5%)	11/62 (18%)	3.8 (1.8 – 8.0)	0.0002
C^*15	14/579 (2%)	7/83 (8%)	3.7 (1.5 – 9.5)	0.010

P value less than 0.017 was considered statistically significant. All p-values are from chi-square tests

^†

Numbers of cases and controls vary by each allele due to incomplete HLA typing.