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Adverse Events
| Maximum grade (no. of patients) | ||||
|---|---|---|---|---|
|
| ||||
| Toxicity | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
| Hematologic | ||||
| Neutropenia | 1 | 16 | 14 | 2 |
| Febrile Neutropenia | 1 | 1 | 0 | 1 |
| Anemia | 0 | 13 | 1 | 0 |
| Thrombocytopenia | 0 | 0 | 0 | 0 |
| Non-hematologic | ||||
| Allergy | 1 | 0 | 0 | 0 |
| Fatigue | 19 | 9 | 0 | 0 |
| Fever | 8 | 4 | 2 | 0 |
| Rigors, chills | 8 | 3 | 0 | 0 |
| Alopecia | 9 | 13 | 0 | 0 |
| Constipation | 9 | 0 | 0 | 0 |
| Diarrhea | 12 | 0 | 0 | 0 |
| Nausea | 28 | 3 | 0 | 0 |
| Vomiting | 7 | 3 | 1 | 0 |
| Sensory Neuropathy | 11 | 6 | 0 | 0 |
| Myalgia / arthralgia | 6 | 8 | 0 | 0 |
| Infection | 0 | 0 | 1 | 2 |
