Table 2.

CIE alters neuronal 3α,5α-THP levels across various brain structures following 8 hr or 72 hr withdrawal.

	8 hr Withdrawal		72 hr Withdrawal
	Air	Ethanol	Air	Ethanol
mPFC	54,711 ± 4990	45,671 ± 2486	53,897 ± 3448	40,415 ± 3622*
CA1	58,952 ± 7703	58,544 ± 10774	142,514 ± 15,040	113,555 ± 11,952
CA3	82,170 ± 9349	78,888 ± 11321	70,094 ± 4820	110,420 ± 14,116*
Polymorph Cell Layer of Dentate Gyrus	25,781 ± 1997	23,289 ± 2356	21,324 ± 2350	21,378 ± 2424
VTA	14,941 ± 1081	10,980 ± 1421*	25,032 ± 3143	17,134 ± 1582*
NAcc core	72,394 ± 2121	70,288 ± 4898	48,175 ± 2465	33,718 ± 2230#
NAcc shell	70,666 ± 2213	66,353 ± 4138	42,134 ± 2917	43,094 ± 2017
DLS	43,683 ± 1195	41,419 ± 3764	37,084 ± 1504	30,209 ± 1614**
DMS	52,310 ± 1539	46,504 ± 3130	45,132 ± 1504	44,681 ± 1614
LA	24,606 ± 1949	17,653 ± 2440*	22,301 ± 2372	16,214 ± 1569*
CeA	23,474 ± 2291	16,582 ± 2015*	12,936 ± 884	13,017 ± 1491
BLA	28,390 ± 2305	24,932 ± 3711	19,016 ± 1687	18,108 ± 1663
PVN	33,149 ± 2800	28,693 ± 2507	23,576 ± 2134	21,038 ±1991
Dorsal BNST	13,824 ± 1802	12,326 ± 1287	11,928 ± 2500	10,540 ± 1464
Ventral BNST	13,474 ± 1573	11,367 ± 1049	19,520 ± 2635	15,723 ± 1818

Data are presented as mean positive pixels/mm² ± SEM of air-exposed or ethanol exposed mice following 8 hr or 72 hr withdrawal (air-exposed n= 10-12; ethanol-exposed n=10-13)

^*p< 0.05

^**p<0.01

^#p<0.0005 compared to respective air-exposed control.